PRAXIS PRECISION MEDICINES INC. 2023-2024 Proxy Voting Records

Description as filed by funds: Election of Class I Directors to serve until the 2027 Annual Meeting of Stockholders, and until their respective successors have been duly elected and qualified: Dean Mitchell

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“Elect Director: Dean Mitchell”): 11,067,526 for, 3,114,657 withheld, per its Form 8-K filed June 6, 2024 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.

Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 78% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.

Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).

Fund voting reports, all 25 managers: 334,906 for, 1,765,925 withheld.

Institutional-manager reports, all 1 managers: 78,100 for.

Description as filed by funds: Election of Class I Directors to serve until the 2027 Annual Meeting of Stockholders, and until their respective successors have been duly elected and qualified: Jill DeSimone

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“Elect Director: Jill DeSimone”): 10,861,923 for, 3,320,260 withheld, per its Form 8-K filed June 6, 2024 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.

Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 77% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.

Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).

Fund voting reports, all 25 managers: 238,798 for, 1,862,033 withheld.

Institutional-manager reports, all 1 managers: 78,100 for.

Description as filed by funds: Approval of amendments to our Amended and Restated Certificate of Incorporation, to give our Board of Directors discretionary authority to effect a reverse stock split of all of the outstanding shares of our Common Stock, at a ratio ranging from any whole number between 1-for-5 and 1-for-25, as determined by our Board in its discretion (the "Reverse Stock Split Proposal").

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“1. Reverse Stock Split”): 85,952,274 for, 21,357,155 against — passed, per its Form 8-K filed November 6, 2023 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 1 – Reverse Stock Split The Company's stockholders approved amendments to the Company's Amended and Restated Certificate of Incorporation to give the Company's Board of Directors discretionary authority to effect a reverse stock split of all of the outstanding shares of the Company's commo…”
Support: 80% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

The 12 asset managers below reported 96,152 for, 6,571,856 against.

Description as filed by funds: Approval of a proposal to adjourn the Special Meeting to a later date or dates, if necessary or appropriate, to permit further solicitation and vote of proxies in the event that there are insufficient votes for, or otherwise in connection with, the approval of the Reverse Stock Split Proposal.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“2. Adjournment”): 85,270,203 for, 22,026,296 against — passed, per its Form 8-K filed November 6, 2023 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 2 – Adjournment The Company's stockholders approved a proposal to adjourn the Special Meeting to a later date or dates, if necessary or appropriate, to permit further solicitation and vote of proxies in the event that there are insufficient votes for, or otherwise in connection with, the a…”
Support: 79% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

The 12 asset managers below reported 96,152 for, 6,571,856 against.

Description as filed by funds: To approve the amendment and restatement of the Company's 2020 Stock Option and Incentive Plan.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“3. Amendment and Restatement of the 2020 Stock Option and Incentive Plan”): 9,080,631 for, 5,097,843 against — passed, per its Form 8-K filed June 6, 2024 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 3 - Amendment and Restatement of the 2020 Stock Option and Incentive Plan The Company's stockholders approved the amendment and restatement of the Company's 2020 Stock Option and Incentive Plan, with the votes cast as follows:”
Support: 64% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).

Fund voting reports, all 25 managers: 2,100,831 against.

Institutional-manager reports, all 1 managers: 78,100 for.

Description as filed by funds: To approve, on an advisory (non- binding) basis, the compensation of the named executive officers as disclosed in the Company's proxy statement for the 2024 Annual Meeting of Stockholders pursuant to the applicable compensation disclosure rules of the SEC, including the compensation tables and narrative discussion.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“4. Advisory Vote on Executive Compensation”): 10,040,059 for, 4,137,994 against — passed, per its Form 8-K filed June 6, 2024 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 4 – Advisory Vote on Executive Compensation The Company's stockholders approved, on an advisory (non-binding) basis, the compensation of the Company's named executive officers, with the votes cast as follows:”
Support: 71% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).

Fund voting reports, all 25 managers: 961,365 for, 1,139,466 against.

No total is shown for the institutional-manager reports: their sum exceeds the company's reported shares outstanding. Showing the 25 largest; every one is in the interactive database (link above).

Description as filed by funds: To ratify the selection of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2024.

PRAXIS PRECISION MEDICINES INC.’s own tally for this item (“2. Ratification of Appointment of Ernst & Young LLP as the Company ' s Independent Registered Public Accounting Firm”): 15,288,730 for, 15,957 against — passed, per its Form 8-K filed June 6, 2024 (Item 5.07).

Reported outcome: Approved, in the filing’s own words: “Proposal 2 – Ratification of Appointment of Ernst & Young LLP as the Company ' s Independent Registered Public Accounting Firm The Company's stockholders ratified the appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December …”
Support: 99.8% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.

Fund voting reports and institutional-manager reports both cover this item. An institutional manager can report shares that a fund it advises also reports, so the two are shown separately below and never added together, and their sum is not shown (fund and manager reports combined may count the same shares twice).

Fund voting reports, all 25 managers: 2,100,831 for.

Institutional-manager reports, all 1 managers: 78,100 for.