Home › Companies › Septerna, Inc. › 2025-2026
At Septerna, Inc.'s shareholder meeting held June 26, 2026, in the 2025-2026 proxy season, 57 asset managers reported how they voted on 3 ballot items in their SEC Form N-PX filings, covering 481 separate fund positions. On the most widely held item on that ballot — To elect two Class II directors to our board of directors, each to serve until our 2029 Annual… — FOR was 85% of the votes cast (FOR divided by FOR plus WITHHELD, because this ballot offered only for and withhold; abstentions, broker non-votes and unvoted shares are excluded because none of them took a side), which is more than half. Whether the item was approved is for the filing to say; that statement has not been read for this item. Source: Septerna, Inc.'s Form 8-K, Item 5.07, filed with the U.S. Securities and Exchange Commission on June 30, 2026.
Download data (CSV): ballot items · votes by manager · column guide.
Compiled from SEC Form N-PX filings and Septerna, Inc.’s Form 8-K, filed June 30, 2026 (Item 5.07 on EDGAR). Page generated November 8, 2026.
Meeting of June 26, 2026: 3 items on Septerna, Inc.’s Form 8-K, filed June 30, 2026: 1 approved · 2 without a stated outcome.
None.
Material dissent: a director nominee under 80% of the votes cast, say-on-pay under 70%, any other item the board put forward under 80%, or a shareholder proposal with more than 50%, on the company’s own Form 8-K tally. How this is decided
Proxy season: 2025-2026
Explore Septerna, Inc. in the interactive database Compare manager voting policies
These tallies are Septerna, Inc.’s own, as disclosed to the U.S. Securities and Exchange Commission on Form 8-K, filed June 30, 2026 (Item 5.07, “Submission of Matters to a Vote of Security Holders”). They cover every share voted at the meeting, not just the funds that file Form N-PX.
| Ballot item | For | Against | Abstain | Withheld | Broker non-votes | Support (of votes cast) | Reported outcome | Voting standard |
|---|---|---|---|---|---|---|---|---|
| Elect Director: Shalini Sharp, M.B.A. | 33,732,317 | -- | -- | 5,808,264 | 1,969,475 | 85% | Not verified | — |
| Elect Director: Jake Simson, Ph.D. | 33,716,857 | -- | -- | 5,823,724 | 1,969,475 | 85% | Not verified | — |
| 2. The appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2026 | 41,207,237 | 4,008 | 298,811 | -- | 0 | 99.9% | Approved | — |
Source: Septerna, Inc., Form 8-K, filed with the SEC on June 30, 2026 — read the filing on EDGAR.
Each item below shows how the 57 asset managers that disclosed a Septerna, Inc. vote in their SEC Form N-PX filings actually voted. Share totals are the shares those managers' funds voted, summed across every fund they report.
Combines 4 wordings of this item as funds reported it.
85% Majority: yes · of votes cast
Description as filed by funds: To elect two Class II directors to our board of directors, each to serve until our 2029 Annual Meeting of Stockholders and until his or her respective successor has been duly elected and qualified, or until his or her earlier death, resignation or removal: Jake Simson
Septerna, Inc.’s own tally for this item (“Elect Director: Jake Simson, Ph.D.”): 33,716,857 for, 5,823,724 withheld, per its Form 8-K filed June 30, 2026 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.
Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 85% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.
The 57 asset managers below reported 4,521,572 for, 1,190,526 withheld, 7 abstained.
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| Vanguard | 1,374,412 | 0 | 7 | 0 | For |
| BlackRock | 932,952 | 0 | 0 | 0 | For |
| PRIMECAP Odyssey Funds | 772,974 | 0 | 0 | 0 | For |
| Fidelity | 593,037 | 0 | 0 | 0 | For |
| DRIEHAUS MUTUAL FUNDS | 0 | 0 | 0 | 554,925 | Withhold |
| Charles Schwab | 194,180 | 0 | 0 | 0 | For |
| State Street | 146,080 | 0 | 0 | 108 | For |
| TRUST FOR PROFESSIONAL MANAGERS | 0 | 0 | 0 | 110,886 | Withhold |
| Prudential/PGIM | 0 | 0 | 0 | 105,663 | Withhold |
| Jackson National | 0 | 0 | 0 | 99,168 | Withhold |
| Goldman Sachs | 92,971 | 0 | 0 | 0 | For |
| Federated Hermes | 82,313 | 0 | 0 | 0 | For |
| RBB FUND, INC. | 0 | 0 | 0 | 77,166 | Withhold |
| Invesco | 61,591 | 0 | 0 | 0 | For |
| HUSSMAN INVESTMENT TRUST | 61,500 | 0 | 0 | 0 | For |
| American Century | 0 | 0 | 0 | 60,138 | Withhold |
| Equitable | 30,686 | 0 | 0 | 11,300 | Mixed |
| JPMorgan | 41,725 | 0 | 0 | 0 | For |
| QUANTITATIVE MASTER SERIES LLC | 36,349 | 0 | 0 | 0 | For |
| Brinker Capital Destinations Trust | 502 | 0 | 0 | 26,247 | Withhold |
| TIAA | 0 | 0 | 0 | 25,798 | Withhold |
| Lincoln Financial | 14,400 | 0 | 0 | 10,100 | Mixed |
| SEI | 18,014 | 0 | 0 | 0 | For |
| AIG/SunAmerica | 0 | 0 | 0 | 17,765 | Withhold |
| Dimensional | 0 | 0 | 0 | 16,325 | Withhold |
Showing the 25 largest of 57 asset managers. All 57 are in the interactive database (link above).
Combines 4 wordings of this item as funds reported it.
85% Majority: yes · of votes cast
Description as filed by funds: To elect two Class II directors to our board of directors, each to serve until our 2029 Annual Meeting of Stockholders and until his or her respective successor has been duly elected and qualified, or until his or her earlier death, resignation or removal: Shalini Sharp
Septerna, Inc.’s own tally for this item (“Elect Director: Shalini Sharp, M.B.A.”): 33,732,317 for, 5,808,264 withheld, per its Form 8-K filed June 30, 2026 (Item 5.07). FOR was more than half of the votes cast. Whether the item passed is for the filing to say; its statement has not been read for this item.
Reported outcome: not verified — the filing’s own statement of the outcome could not be identified for this item.
Support: 85% of votes cast — FOR ÷ (FOR + WITHHELD); abstentions and broker non-votes are excluded.
The 57 asset managers below reported 4,543,754 for, 1,168,345 withheld, 7 abstained.
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| Vanguard | 1,373,386 | 0 | 7 | 1,026 | For |
| BlackRock | 932,952 | 0 | 0 | 0 | For |
| PRIMECAP Odyssey Funds | 772,974 | 0 | 0 | 0 | For |
| Fidelity | 593,037 | 0 | 0 | 0 | For |
| DRIEHAUS MUTUAL FUNDS | 0 | 0 | 0 | 554,925 | Withhold |
| Charles Schwab | 194,180 | 0 | 0 | 0 | For |
| State Street | 146,080 | 0 | 0 | 108 | For |
| TRUST FOR PROFESSIONAL MANAGERS | 0 | 0 | 0 | 110,886 | Withhold |
| Prudential/PGIM | 0 | 0 | 0 | 105,663 | Withhold |
| Jackson National | 0 | 0 | 0 | 99,168 | Withhold |
| Goldman Sachs | 92,971 | 0 | 0 | 0 | For |
| Federated Hermes | 82,313 | 0 | 0 | 0 | For |
| RBB FUND, INC. | 0 | 0 | 0 | 77,166 | Withhold |
| Invesco | 61,591 | 0 | 0 | 0 | For |
| HUSSMAN INVESTMENT TRUST | 61,500 | 0 | 0 | 0 | For |
| American Century | 0 | 0 | 0 | 60,138 | Withhold |
| Equitable | 30,686 | 0 | 0 | 11,300 | Mixed |
| JPMorgan | 41,725 | 0 | 0 | 0 | For |
| QUANTITATIVE MASTER SERIES LLC | 36,349 | 0 | 0 | 0 | For |
| Brinker Capital Destinations Trust | 502 | 0 | 0 | 26,247 | Withhold |
| TIAA | 25,798 | 0 | 0 | 0 | For |
| Lincoln Financial | 14,400 | 0 | 0 | 10,100 | Mixed |
| SEI | 18,014 | 0 | 0 | 0 | For |
| AIG/SunAmerica | 0 | 0 | 0 | 17,765 | Withhold |
| Dimensional | 0 | 0 | 0 | 16,325 | Withhold |
Showing the 25 largest of 57 asset managers. All 57 are in the interactive database (link above).
Combines 2 wordings of this item as funds reported it.
99.9% Approved · of votes cast
Description as filed by funds: To ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2026; and
Septerna, Inc.’s own tally for this item (“2. The appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2026”): 41,207,237 for, 4,008 against — passed, per its Form 8-K filed June 30, 2026 (Item 5.07).
Reported outcome: Approved, in the filing’s own words: “Proposal No. 2 The Company's stockholders ratified the appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2026.”
Support: 99.9% of votes cast — FOR ÷ (FOR + AGAINST); abstentions and broker non-votes are excluded.
The 57 asset managers below reported 5,712,106 for.
| Asset manager | For | Against | Abstain | Withheld | Vote |
|---|---|---|---|---|---|
| Vanguard | 1,374,419 | 0 | 0 | 0 | For |
| BlackRock | 932,952 | 0 | 0 | 0 | For |
| PRIMECAP Odyssey Funds | 772,974 | 0 | 0 | 0 | For |
| Fidelity | 593,037 | 0 | 0 | 0 | For |
| DRIEHAUS MUTUAL FUNDS | 554,925 | 0 | 0 | 0 | For |
| Charles Schwab | 194,180 | 0 | 0 | 0 | For |
| State Street | 146,188 | 0 | 0 | 0 | For |
| TRUST FOR PROFESSIONAL MANAGERS | 110,886 | 0 | 0 | 0 | For |
| Prudential/PGIM | 105,663 | 0 | 0 | 0 | For |
| Jackson National | 99,168 | 0 | 0 | 0 | For |
| Goldman Sachs | 92,971 | 0 | 0 | 0 | For |
| Federated Hermes | 82,313 | 0 | 0 | 0 | For |
| RBB FUND, INC. | 77,166 | 0 | 0 | 0 | For |
| Invesco | 61,591 | 0 | 0 | 0 | For |
| HUSSMAN INVESTMENT TRUST | 61,500 | 0 | 0 | 0 | For |
| American Century | 60,138 | 0 | 0 | 0 | For |
| Equitable | 41,986 | 0 | 0 | 0 | For |
| JPMorgan | 41,725 | 0 | 0 | 0 | For |
| QUANTITATIVE MASTER SERIES LLC | 36,349 | 0 | 0 | 0 | For |
| Brinker Capital Destinations Trust | 26,749 | 0 | 0 | 0 | For |
| TIAA | 25,798 | 0 | 0 | 0 | For |
| Lincoln Financial | 24,500 | 0 | 0 | 0 | For |
| SEI | 18,014 | 0 | 0 | 0 | For |
| AIG/SunAmerica | 17,765 | 0 | 0 | 0 | For |
| Dimensional | 16,325 | 0 | 0 | 0 | For |
Showing the 25 largest of 57 asset managers. All 57 are in the interactive database (link above).
Ranked separately for each type of Form N-PX report. An institutional manager can report shares that a fund it advises also reports, so the two tables can list the same shares and are never added together. Each is ranked by the shares voted on the item that the most managers of that type reported, shown as a share of the 45,075,533 shares outstanding at the time of that meeting.
| # | Asset manager | % of shares outstanding |
|---|---|---|
| 1 | Vanguard | 3.05% |
| 2 | BlackRock | 2.07% |
| 3 | PRIMECAP Odyssey Funds | 1.71% |
| 4 | Fidelity | 1.32% |
| 5 | DRIEHAUS MUTUAL FUNDS | 1.23% |
| 6 | Charles Schwab | 0.43% |
| 7 | State Street | 0.32% |
| 8 | TRUST FOR PROFESSIONAL MANAGERS | 0.25% |
| 9 | Prudential/PGIM | 0.23% |
| 10 | Jackson National | 0.22% |
As disclosed to the SEC in Form 13F (quarter-end holdings of 30 large managers), Schedules 13D and 13G (beneficial ownership above 5%) and the company’s own proxy statement (DEF 14A). Each row names its form.
| Holder | % outstanding | Disclosure |
|---|---|---|
| Entities Affiliated with Third Rock Ventures | 23.23% | DEF14A |
| Entities Affiliated with RA Capital | 15.57% | DEF14A |
| RA Capital Management, L.P. | 12.26% | 13D |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 9.83% | 13G |
| Goldman Sachs | 6.45% | 13F |
| Samsara BioCapital LP | 6.14% | DEF14A |
| BlackRock | 4.04% | 13F |
| BVF PARTNERS L P/IL | 3.82% | 13G |
| Vanguard Group | 3.35% | 13F |
| Jeffrey Finer, M.D., Ph.D. | 3.23% | DEF14A |
Percentages above are of 45,075,533 shares outstanding, as reported by Septerna, Inc. on its Form 10-Q dated May 7, 2026 (see the filing on EDGAR). This is the count contemporaneous with the 2025-2026 meeting, not today’s. Each holding is as of its own filing, which may be dated before or after the meeting.
Every figure above is derived from filings made with the US Securities and Exchange Commission: Form N-PX, in which registered funds disclose how they voted every proxy and institutional managers disclose their votes on executive pay (say-on-pay, say-on-frequency and golden parachutes), and Form 8-K Item 5.07, in which the company reports its own meeting results. Shares outstanding are taken from Septerna, Inc.’s 10-Q dated May 7, 2026. This page is a static snapshot rebuilt weekly on November 8, 2026; a live search always shows the current data.
Septerna, Inc. proxy season coverage: 2025-2026 (this page).
proxyvotesnow.com, “Septerna (SEPN) 2026 Annual Meeting: Vote Results & How Funds Voted”, https://proxyvotesnow.com/company/septerna-inc/2026 (version of November 9, 2026). Derived from SEC Form N-PX and Form 8-K filings; tables licensed CC BY 4.0. Licence: CC BY 4.0.